New Article: Macrolide resistance through ribosomal duplication events in a commensal

I am so excited to see this work finally published! This study was designed and conducted by the students in my Genomics class at RIT during the fall semester of 2020. In this work, students experimentally evolved resistance to an antibiotic in a Neisseria commensal species. They then sequenced the genomes of resistant lineages and found mutations that caused resistance converged on short sequence duplication events in ribosomal genes. Since Neisseria commensals share resistance with their pathogenic relatives (one of which is the bacterial pathogen that causes gonorrhea), it is important to understand the paths to resistance in these species too!
Congrats to all involved!  An especially big thank you to André O. Hudson for your help and guidance!

​https://journals.plos.org/plosone/article?id=10.1371/journal.pone.0262370